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Bridging the structure gap between pellets in artificial dissolution media and in gastro-intestinal tract in rats
Changes in structure of oral solid dosage forms (OSDF) elementally determine the drug release and its therapeutic effects. In this research, synchrotron radiation X-ray micro-computed tomography was utilized to visualize the 3D structure of enteric coated pellets recovered from the gastrointestinal...
Autores principales: | Sun, Hongyu, He, Siyu, Wu, Li, Cao, Zeying, Sun, Xian, Xu, Mingwei, Lu, Shan, Xu, Mingdi, Ning, Baoming, Sun, Huimin, Xiao, Tiqiao, York, Peter, Xu, Xu, Yin, Xianzhen, Zhang, Jiwen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8799995/ https://www.ncbi.nlm.nih.gov/pubmed/35127389 http://dx.doi.org/10.1016/j.apsb.2021.05.010 |
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