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A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes

Chromatin-modifying complexes containing histone deacetylase (HDAC) activities play critical roles in the regulation of gene transcription in eukaryotes. These complexes are thought to lack intrinsic DNA-binding activity, but according to a well-established paradigm, they are recruited via protein–p...

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Detalles Bibliográficos
Autores principales: Marcum, Ryan Dale, Hsieh, Joseph, Giljen, Maksim, Justice, Emily, Daffern, Nicolas, Zhang, Yongbo, Radhakrishnan, Ishwar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800102/
https://www.ncbi.nlm.nih.gov/pubmed/34979096
http://dx.doi.org/10.1016/j.jbc.2021.101558