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A capped Tudor domain within a core subunit of the Sin3L/Rpd3L histone deacetylase complex binds to nucleic acid G-quadruplexes
Chromatin-modifying complexes containing histone deacetylase (HDAC) activities play critical roles in the regulation of gene transcription in eukaryotes. These complexes are thought to lack intrinsic DNA-binding activity, but according to a well-established paradigm, they are recruited via protein–p...
Autores principales: | Marcum, Ryan Dale, Hsieh, Joseph, Giljen, Maksim, Justice, Emily, Daffern, Nicolas, Zhang, Yongbo, Radhakrishnan, Ishwar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800102/ https://www.ncbi.nlm.nih.gov/pubmed/34979096 http://dx.doi.org/10.1016/j.jbc.2021.101558 |
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