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Selective activation of TRPA1 ion channels by nitrobenzene skin sensitizers DNFB and DNCB

2, 4-dinitrofluorobenzene (DNFB) and 2, 4-dinitrochlorobenzene (DNCB) are well known as skin sensitizers that can cause dermatitis. DNFB has shown to more potently sensitize skin; however, how DNFB and DNCB cause skin inflammation at a molecular level and why this difference in their sensitization a...

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Detalles Bibliográficos
Autores principales: Wu, Han, Niu, Canyang, Qu, Yaxuan, Sun, Xiaoying, Wang, KeWei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800105/
https://www.ncbi.nlm.nih.gov/pubmed/34973335
http://dx.doi.org/10.1016/j.jbc.2021.101555