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Structural determinants of the interactions of catechins with Aβ oligomers and lipid membranes

The aberrant self-assembly of intrinsically disordered proteins (IDPs) into soluble oligomers and their interactions with biological membranes underlie the pathogenesis of numerous neurodegenerative diseases, including Alzheimer’s disease. Catechins have emerged as useful tools to reduce the toxicit...

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Detalles Bibliográficos
Autores principales: Ahmed, Rashik, Huang, Jinfeng, Lifshitz, Romi, Martinez Pomier, Karla, Melacini, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800114/
https://www.ncbi.nlm.nih.gov/pubmed/34929173
http://dx.doi.org/10.1016/j.jbc.2021.101502