Montelukast is a dual-purpose inhibitor of SARS-CoV-2 infection and virus-induced IL-6 expression identified by structure-based drug repurposing

Drug-repurposing has been instrumental to identify drugs preventing SARS-CoV-2 replication or attenuating the disease course of COVID-19. Here, we identify through structure-based drug-repurposing a dual-purpose inhibitor of SARS-CoV-2 infection and of IL-6 production by immune cells. We created a c...

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Detalles Bibliográficos
Autores principales: Luedemann, Max, Stadler, Daniela, Cheng, Cho-Chin, Protzer, Ulrike, Knolle, Percy A., Donakonda, Sainitin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800171/
https://www.ncbi.nlm.nih.gov/pubmed/35126884
http://dx.doi.org/10.1016/j.csbj.2022.01.024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800171/
https://www.ncbi.nlm.nih.gov/pubmed/35126884
http://dx.doi.org/10.1016/j.csbj.2022.01.024

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