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MORPHIOUS: an unsupervised machine learning workflow to detect the activation of microglia and astrocytes

BACKGROUND: In conditions of brain injury and degeneration, defining microglial and astrocytic activation using cellular markers alone remains a challenging task. We developed the MORPHIOUS software package, an unsupervised machine learning workflow which can learn the morphologies of non-activated...

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Detalles Bibliográficos
Autores principales:	Silburt, Joseph, Aubert, Isabelle
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800241/ https://www.ncbi.nlm.nih.gov/pubmed/35093113 http://dx.doi.org/10.1186/s12974-021-02376-9

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