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G protein-coupled receptor kinase 3 modulates mesenchymal stem cell proliferation and differentiation through sphingosine-1-phosphate receptor regulation

BACKGROUND: The bone marrow niche supports hematopoietic cell development through intimate contact with multipotent stromal mesenchymal stem cells; however, the intracellular signaling, function, and regulation of such supportive niche cells are still being defined. Our study was designed to underst...

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Detalles Bibliográficos
Autores principales: Brozowski, Jaime M., Timoshchenko, Roman G., Serafin, D. Stephen, Allyn, Brittney, Koontz, Jessica, Rabjohns, Emily M., Rampersad, Rishi R., Ren, Yinshi, Eudy, Amanda M., Harris, Taylor F., Abraham, David, Mattox, Daniel, Rubin, Clinton T., Hilton, Matthew J., Rubin, Janet, Allbritton, Nancy L., Billard, Matthew J., Tarrant, Teresa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800243/
https://www.ncbi.nlm.nih.gov/pubmed/35093170
http://dx.doi.org/10.1186/s13287-022-02715-4