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An integrative multi-omics analysis based on liquid–liquid phase separation delineates distinct subtypes of lower-grade glioma and identifies a prognostic signature

BACKGROUND: Emerging evidences have indicated that the aberrant liquid–liquid phase separation (LLPS) leads to the dysfunction of biomolecular condensates, thereby contributing to the tumorigenesis and progression. Nevertheless, it remains unclear whether or how the LLPS of specific molecules affect...

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Detalles Bibliográficos
Autores principales: Zheng, Jianglin, Wu, Zhipeng, Qiu, Yue, Wang, Xuan, Jiang, Xiaobing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800244/
https://www.ncbi.nlm.nih.gov/pubmed/35093128
http://dx.doi.org/10.1186/s12967-022-03266-1