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Thioacetamide promotes osteoclast transformation of bone marrow macrophages by influencing PI3K/AKT pathways
BACKGROUND: Osteoclast cell increase is a major risk factor for osteoporosis and degenerative bone and joint diseases. At present, RANKL and M-CSF are commonly used to induce osteoclastogenesis. Thioacetamide (TAA) can lead to many types of liver and kidney damage, but less attention has been paid t...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800259/ https://www.ncbi.nlm.nih.gov/pubmed/35093114 http://dx.doi.org/10.1186/s13018-022-02938-4 |