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Thioacetamide promotes osteoclast transformation of bone marrow macrophages by influencing PI3K/AKT pathways

BACKGROUND: Osteoclast cell increase is a major risk factor for osteoporosis and degenerative bone and joint diseases. At present, RANKL and M-CSF are commonly used to induce osteoclastogenesis. Thioacetamide (TAA) can lead to many types of liver and kidney damage, but less attention has been paid t...

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Detalles Bibliográficos
Autores principales:	Jin, XiaoLi, Li, Yang, Yang, Yayang, Shen, Hao, Chen, Jin, Xu, Bin, Xu, Jian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800259/ https://www.ncbi.nlm.nih.gov/pubmed/35093114 http://dx.doi.org/10.1186/s13018-022-02938-4

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