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The ILEI/LIFR complex induces EMT via the Akt and ERK pathways in renal interstitial fibrosis
BACKGROUND: Chronic kidney disease (CKD) is characterized by high morbidity and mortality and is difficult to cure. Renal interstitial fibrosis (RIF) is a major determinant of, and commonly occurs within, CKD progression. Epithelial mesenchymal transition (EMT) has been identified as a crucial proce...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800269/ https://www.ncbi.nlm.nih.gov/pubmed/35093095 http://dx.doi.org/10.1186/s12967-022-03265-2 |