Targeting the A(3) adenosine receptor to prevent and reverse chemotherapy-induced neurotoxicities in mice

Cisplatin is used to combat solid tumors. However, patients treated with cisplatin often develop cognitive impairments, sensorimotor deficits, and peripheral neuropathy. There is no FDA-approved treatment for these neurotoxicities. We investigated the capacity of a highly selective A(3) adenosine re...

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Detalles Bibliográficos
Autores principales: Singh, Anand Kumar, Mahalingam, Rajasekaran, Squillace, Silvia, Jacobson, Kenneth A., Tosh, Dilip K., Dharmaraj, Shruti, Farr, Susan A., Kavelaars, Annemieke, Salvemini, Daniela, Heijnen, Cobi J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800287/
https://www.ncbi.nlm.nih.gov/pubmed/35093182
http://dx.doi.org/10.1186/s40478-022-01315-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800287/
https://www.ncbi.nlm.nih.gov/pubmed/35093182
http://dx.doi.org/10.1186/s40478-022-01315-w

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