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Making sense of the linear genome, gene function and TADs

BACKGROUND: Topologically associating domains (TADs) are thought to act as functional units in the genome. TADs co-localise genes and their regulatory elements as well as forming the unit of genome switching between active and inactive compartments. This has led to the speculation that genes which a...

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Detalles Bibliográficos
Autores principales: Long, Helen S., Greenaway, Simon, Powell, George, Mallon, Ann-Marie, Lindgren, Cecilia M., Simon, Michelle M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800309/
https://www.ncbi.nlm.nih.gov/pubmed/35090532
http://dx.doi.org/10.1186/s13072-022-00436-9