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Making sense of the linear genome, gene function and TADs
BACKGROUND: Topologically associating domains (TADs) are thought to act as functional units in the genome. TADs co-localise genes and their regulatory elements as well as forming the unit of genome switching between active and inactive compartments. This has led to the speculation that genes which a...
Autores principales: | Long, Helen S., Greenaway, Simon, Powell, George, Mallon, Ann-Marie, Lindgren, Cecilia M., Simon, Michelle M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800309/ https://www.ncbi.nlm.nih.gov/pubmed/35090532 http://dx.doi.org/10.1186/s13072-022-00436-9 |
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