Single-cell transcriptomic analysis reveals a novel cell state and switching genes during hepatic stellate cell activation in vitro

BACKGROUND: The transformation of hepatic stellate cell (HSC) to myofibroblast is a key event during liver fibrogenesis. However, the differentiation trajectory of HSC-to-myofibroblast transition and the switching genes during this process remains not well understood. METHODS: We applied single-cell...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Hua, Zheng, Shaoping, Jiang, Hongbo, Wang, Xuejia, Zhou, Fengqin, Weng, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800312/
https://www.ncbi.nlm.nih.gov/pubmed/35093101
http://dx.doi.org/10.1186/s12967-022-03263-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800312/
https://www.ncbi.nlm.nih.gov/pubmed/35093101
http://dx.doi.org/10.1186/s12967-022-03263-4

Ejemplares similares