ATAD3A mediates activation of RAS-independent mitochondrial ERK1/2 signaling, favoring head and neck cancer development

BACKGROUND: Targeting mitochondrial oncoproteins presents a new concept in the development of effective cancer therapeutics. ATAD3A is a nuclear-encoded mitochondrial enzyme contributing to mitochondrial dynamics, cholesterol metabolism, and signal transduction. However, its impact and underlying re...

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Detalles Bibliográficos
Autores principales: Lang, Liwei, Loveless, Reid, Dou, Juan, Lam, Tiffany, Chen, Alex, Wang, Fang, Sun, Li, Juarez, Jakeline, Qin, Zhaohui Steve, Saba, Nabil F., Shay, Chloe, Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800319/
https://www.ncbi.nlm.nih.gov/pubmed/35093151
http://dx.doi.org/10.1186/s13046-022-02274-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800319/
https://www.ncbi.nlm.nih.gov/pubmed/35093151
http://dx.doi.org/10.1186/s13046-022-02274-9

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