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TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is a progressive neurodegenerative disorder. Its molecular mechanism is still unclear, and pharmacological treatments are unsatisfactory. Transient receptor potential vanilloid 4 (TRPV4) is a nonselective Ca(2+) channel. It has recently emerged as a critical risk...

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Detalles Bibliográficos
Autores principales: Liu, Na, Bai, Liping, Lu, Zhipeng, Gu, Rou, Zhao, Dongdong, Yan, Fang, Bai, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800324/
https://www.ncbi.nlm.nih.gov/pubmed/35093118
http://dx.doi.org/10.1186/s12974-022-02382-5