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Human olfactory mesenchymal stromal cell transplantation ameliorates experimental autoimmune encephalomyelitis revealing an inhibitory role for IL16 on myelination

One of the therapeutic approaches for the treatment of the autoimmune demyelinating disease, multiple sclerosis (MS) is bone marrow mesenchymal stromal cell (hBM-MSCs) transplantation. However, given their capacity to enhance myelination in vitro, we hypothesised that human olfactory mucosa-derived...

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Detalles Bibliográficos
Autores principales: Lindsay, Susan L., Molęda, Aleksandra M., MacLellan, Lindsay M., Keh, Siew Min, McElroy, Daniel E., Linington, Christopher, Goodyear, Carl S., Barnett, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800340/
https://www.ncbi.nlm.nih.gov/pubmed/35093166
http://dx.doi.org/10.1186/s40478-022-01316-9