CD19-CAR T cells undergo exhaustion DNA methylation programming in patients with acute lymphoblastic leukemia

CD19-CAR T cell therapy has evolved into the standard of care for relapsed/refractory B cell acute lymphoblastic leukemia (ALL); however, limited persistence of the CAR T cells enables tumor relapse for many patients. To gain a deeper understanding of the molecular characteristics associated with CA...

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Detalles Bibliográficos
Autores principales: Zebley, Caitlin C., Brown, Charmaine, Mi, Tian, Fan, Yiping, Alli, Shanta, Boi, Shannon, Galletti, Giovanni, Lugli, Enrico, Langfitt, Deanna, Metais, Jean-Yves, Lockey, Timothy, Meagher, Michael, Triplett, Brandon, Talleur, Aimee C., Gottschalk, Stephen, Youngblood, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800370/
https://www.ncbi.nlm.nih.gov/pubmed/34852226
http://dx.doi.org/10.1016/j.celrep.2021.110079

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800370/
https://www.ncbi.nlm.nih.gov/pubmed/34852226
http://dx.doi.org/10.1016/j.celrep.2021.110079

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