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The mutational dynamics of the SARS-CoV-2 virus in serial passages in vitro

Since its outbreak in 2019, Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) keeps surprising the medical community by evolving diverse immune escape mutations in a rapid and effective manner. To gain deeper insight into mutation frequency and dynamics, we isolated ten ancestral strains...

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Detalles Bibliográficos
Autores principales: Sonnleitner, Sissy Therese, Sonnleitner, Stefanie, Hinterbichler, Eva, Halbfurter, Hannah, Kopecky, Dominik B.C., Koblmüller, Stephan, Sturmbauer, Christian, Posch, Wilfried, Walder, Gernot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wuhan Institute of Virology, Chinese Academy of Sciences 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800542/
https://www.ncbi.nlm.nih.gov/pubmed/35277373
http://dx.doi.org/10.1016/j.virs.2022.01.029