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Recombinant VLPs empower RBM peptides showing no immunogenicity in native SARS-COV-2 protein to elicit a robust neutralizing antibody response

New SARS-COV-2 vaccine strategies are still urgently needed, especially for emerging virus mutations and variants. In this study, we focused on analyzing the antigenicity and vaccine potency of linear peptide epitopes located in receptor binding motif (RBM) of spike (S) protein. Nine 12 to 16-mer ov...

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Detalles Bibliográficos
Autores principales: Long, Qiong, Yang, Ying, Yang, Mengli, Bai, Hongmei, Sun, Wenjia, Yang, Xu, Huang, Weiwei, Li, Duo, Ma, Yanbing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800570/
https://www.ncbi.nlm.nih.gov/pubmed/35104670
http://dx.doi.org/10.1016/j.nano.2022.102527