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Overcoming Resistance to Kinase Inhibitors: The Paradigm of Chronic Myeloid Leukemia

Protein kinases (PKs) play crucial roles in cellular proliferation and survival, hence their deregulation is a common event in the pathogenesis of solid and hematologic malignancies. Targeting PKs has been a promising strategy in cancer treatment, and there are now a variety of approved anticancer d...

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Detalles Bibliográficos
Autores principales: De Santis, Sara, Monaldi, Cecilia, Mancini, Manuela, Bruno, Samantha, Cavo, Michele, Soverini, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800859/
https://www.ncbi.nlm.nih.gov/pubmed/35115784
http://dx.doi.org/10.2147/OTT.S289306