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Sensitization of primary cultures from rat dorsal root ganglia with lipopolysaccharide (LPS) requires a robust inflammatory response

OBJECTIVE: We investigated whether it is possible to induce a state of “LPS-sensitization” in neurons of primary cultures from rat dorsal root ganglia by pre-treatment with ultra-low doses of LPS. METHODS: DRG primary cultures were pre-treated with low to ultra-low doses of LPS (0.001–0.1 µg/ml) for...

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Detalles Bibliográficos
Autores principales: Nürnberger, Franz, Leisengang, Stephan, Ott, Daniela, Murgott, Jolanta, Gerstberger, Rüdiger, Rummel, Christoph, Roth, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8800878/
https://www.ncbi.nlm.nih.gov/pubmed/34940887
http://dx.doi.org/10.1007/s00011-021-01534-2