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FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and one of the major causes of cancer-related death. Thymidylate synthase (TYMS) catalyzes the methylation of deoxy guanosine to deoxy thymidylate, which is a crucial gene for DNA repair and replication. Thus,...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801073/ https://www.ncbi.nlm.nih.gov/pubmed/35093082 http://dx.doi.org/10.1186/s12935-021-02372-2 |