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FOXM1-induced TYMS upregulation promotes the progression of hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and one of the major causes of cancer-related death. Thymidylate synthase (TYMS) catalyzes the methylation of deoxy guanosine to deoxy thymidylate, which is a crucial gene for DNA repair and replication. Thus,...

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Detalles Bibliográficos
Autores principales: Wang, Liang, Shi, Caiyan, Yu, Jie, Xu, Yilin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801073/
https://www.ncbi.nlm.nih.gov/pubmed/35093082
http://dx.doi.org/10.1186/s12935-021-02372-2