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Histone deacetylase inhibitors attenuated interleukin-1β-induced chondrogenesis inhibition in synovium-derived mesenchymal stem cells of the temporomandibular joint

AIMS: In the repair of condylar cartilage injury, synovium-derived mesenchymal stem cells (SMSCs) migrate to an injured site and differentiate into cartilage. This study aimed to confirm that histone deacetylase (HDAC) inhibitors, which alleviate arthritis, can improve chondrogenesis inhibited by IL...

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Detalles Bibliográficos
Autores principales: Liao, Wen-ting, Sun, Jia-dong, Wang, Yun, He, Yi-qing, Su, Kai, Lu, Yun-yang, Liao, Guiqing, Sun, Yang-peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The British Editorial Society of Bone & Joint Surgery 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801172/
https://www.ncbi.nlm.nih.gov/pubmed/35084211
http://dx.doi.org/10.1302/2046-3758.111.BJR-2021-0059.R1