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Renal effects of SGLT2 inhibitors in cardiovascular patients with and without chronic kidney disease: focus on heart failure and renal outcomes

The kidney has a prominent role in maintaining glucose homeostasis by using glucose as a metabolic substrate. This occurs by generating glucose through gluconeogenesis, and by reuptaking filtered glucose through the sodium–glucose cotransporters SGLT1 and SGLT2 located in the proximal tubule. In rec...

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Detalles Bibliográficos
Autores principales: Gronda, Edoardo G., Vanoli, Emilio, Iacoviello, Massimo, Urbinati, Stefano, Caldarola, Pasquale, Colivicchi, Furio, Gabrielli, Domenico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801273/
https://www.ncbi.nlm.nih.gov/pubmed/35098383
http://dx.doi.org/10.1007/s10741-021-10211-9