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Efficient gene editing through an intronic selection marker in cells

BACKGROUND: Gene editing technology has provided researchers with the ability to modify genome sequences in almost all eukaryotes. Gene-edited cell lines are being used with increasing frequency in both bench research and targeted therapy. However, despite the great importance and universality of ge...

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Detalles Bibliográficos
Autores principales: Wang, Shang, Li, Yuqing, Zhong, Li, Wu, Kai, Zhang, Ruhua, Kang, Tiebang, Wu, Song, Wu, Yuanzhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801403/
https://www.ncbi.nlm.nih.gov/pubmed/35098362
http://dx.doi.org/10.1007/s00018-022-04152-1