Awakening sleeper cells: a narrative review on bacterial magic spot synthetases as potential drug targets to overcome persistence

Magic spot synthetases are emerging targets to overcome persistence caused by stringent response. The ‘stringent response’ is a bacterial stress survival mechanism, which results in the accumulation of alarmones (also called Magic spots) leading to the formation of dormant persister cells. These ‘sl...

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Detalles Bibliográficos
Autores principales: Veetilvalappil, Vimal Venu, Aranjani, Jesil Mathew, Mahammad, Fayaz Shaik, Joseph, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801413/
https://www.ncbi.nlm.nih.gov/pubmed/34787710
http://dx.doi.org/10.1007/s00294-021-01221-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801413/
https://www.ncbi.nlm.nih.gov/pubmed/34787710
http://dx.doi.org/10.1007/s00294-021-01221-z

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