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The Signaling and Pharmacology of the Dopamine D1 Receptor

The dopamine D1 receptor (D1R) is a Gα(s/olf)-coupled GPCR that is expressed in the midbrain and forebrain, regulating motor behavior, reward, motivational states, and cognitive processes. Although the D1R was initially identified as a promising drug target almost 40 years ago, the development of cl...

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Detalles Bibliográficos
Autores principales: Jones-Tabah, Jace, Mohammad, Hanan, Paulus, Emma G., Clarke, Paul B. S., Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801442/
https://www.ncbi.nlm.nih.gov/pubmed/35110997
http://dx.doi.org/10.3389/fncel.2021.806618