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The Signaling and Pharmacology of the Dopamine D1 Receptor
The dopamine D1 receptor (D1R) is a Gα(s/olf)-coupled GPCR that is expressed in the midbrain and forebrain, regulating motor behavior, reward, motivational states, and cognitive processes. Although the D1R was initially identified as a promising drug target almost 40 years ago, the development of cl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801442/ https://www.ncbi.nlm.nih.gov/pubmed/35110997 http://dx.doi.org/10.3389/fncel.2021.806618 |