Heparan sulfate is necessary for the early formation of nascent fibronectin and collagen I fibrils at matrix assembly sites

Fibronectin (FN), an essential component of the extracellular matrix (ECM), is assembled via a cell-mediated process in which integrin receptors bind secreted FN and mediate its polymerization into fibrils that extend between cells, ultimately forming an insoluble matrix. Our previous work using mut...

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Detalles Bibliográficos
Autores principales: Hill, Katherine E., Lovett, Benjamin M., Schwarzbauer, Jean E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801470/
https://www.ncbi.nlm.nih.gov/pubmed/34890641
http://dx.doi.org/10.1016/j.jbc.2021.101479

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801470/
https://www.ncbi.nlm.nih.gov/pubmed/34890641
http://dx.doi.org/10.1016/j.jbc.2021.101479

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