Immune Checkpoint LAG3 and Its Ligand FGL1 in Cancer

LAG3 is the most promising immune checkpoint next to PD-1 and CTLA-4. High LAG3 and FGL1 expression boosts tumor growth by inhibiting the immune microenvironment. This review comprises four sections presenting the structure/expression, interaction, biological effects, and clinical application of LAG...

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Detalles Bibliográficos
Autores principales: Shi, An-Ping, Tang, Xi-Yang, Xiong, Yan-Lu, Zheng, Kai-Fu, Liu, Yu-Jian, Shi, Xian-Gui, Lv, Yao, Jiang, Tao, Ma, Nan, Zhao, Jin-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801495/
https://www.ncbi.nlm.nih.gov/pubmed/35111155
http://dx.doi.org/10.3389/fimmu.2021.785091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801495/
https://www.ncbi.nlm.nih.gov/pubmed/35111155
http://dx.doi.org/10.3389/fimmu.2021.785091

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