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Neuroprotective Effects of a Small Mitochondrially-Targeted Tetrapeptide Elamipretide in Neurodegeneration

Neural mitochondrial dysfunction, neural oxidative stress, chronic neuroinflammation, toxic protein accumulation, and neural apoptosis are common causes of neurodegeneration. Elamipretide, a small mitochondrially-targeted tetrapeptide, exhibits therapeutic effects and safety in several mitochondria-...

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Detalles Bibliográficos
Autores principales: Nhu, Nguyen Thanh, Xiao, Shu-Yun, Liu, Yijie, Kumar, V. Bharath, Cui, Zhen-Yang, Lee, Shin-Da
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801496/
https://www.ncbi.nlm.nih.gov/pubmed/35111001
http://dx.doi.org/10.3389/fnint.2021.747901