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Novel Mechanisms of Anthracycline-Induced Cardiovascular Toxicity: A Focus on Thrombosis, Cardiac Atrophy, and Programmed Cell Death

Anthracycline antineoplastic agents such as doxorubicin are widely used and highly effective component of adjuvant chemotherapy for breast cancer and curative regimens for lymphomas, leukemias, and sarcomas. The primary dose-limiting adverse effect of anthracyclines is cardiotoxicity that typically...

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Detalles Bibliográficos
Autores principales: Antoniak, Silvio, Phungphong, Sukanya, Cheng, Zhaokang, Jensen, Brian C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801506/
https://www.ncbi.nlm.nih.gov/pubmed/35111832
http://dx.doi.org/10.3389/fcvm.2021.817977