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Surgical method to prevent early death of neonatal rat pups with Hirschsprung disease, thus permitting development of long-term therapeutic approaches

Hirschsprung disease occurs when children are born with no intrinsic nerve cells in varying lengths of the large intestine. In the most severe cases, neurons are also missing from the distal part of the small intestine. Nerve-mediated relaxation of the aganglionic bowel fails and fecal matter accumu...

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Detalles Bibliográficos
Autores principales: Stamp, Lincon A, Lei, Enie, Liew, Jamie J M, Pustovit, Ruslan V, Hao, Marlene M, Croaker, David H, Furness, John B, Adams, Cameron D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801716/
https://www.ncbi.nlm.nih.gov/pubmed/35111975
http://dx.doi.org/10.1093/biomethods/bpac004