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Enhancement of proliferation of human umbilical cord blood–derived CD34(+) hematopoietic stem cells by a combination of hyper-interleukin-6 and small molecules

Umbilical cord blood (UCB) is an alternative source of allogeneic hematopoietic stem cells (HSCs) for transplantation to treat various hematological disorders. The major limitation to the use of UCB-derived HSCs (UCB–HSCs) in transplantation, however, is the low numbers of HSCs in a unit of cord blo...

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Detalles Bibliográficos
Autores principales: Park, Yo Seph, Lee, Yukyeong, Choi, Na Young, Hwang, Han Sung, Rose-John, Stefan, Zenke, Martin, Ko, Kinarm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801758/
https://www.ncbi.nlm.nih.gov/pubmed/35146134
http://dx.doi.org/10.1016/j.bbrep.2022.101214