Engineering Escherichia coli for efficient aerobic conversion of glucose to fumaric acid

Escherichia coli was engineered for efficient aerobic conversion of glucose to fumaric acid. A novel design for biosynthesis of the target product through the modified TCA cycle rather than via glyoxylate shunt, implying oxaloacetate formation from pyruvate and artificial channelling of 2-ketoglutar...

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Detalles Bibliográficos
Autores principales: Skorokhodova, Alexandra Yu., Gulevich, Andrey Yu., Debabov, Vladimir G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801760/
https://www.ncbi.nlm.nih.gov/pubmed/35145886
http://dx.doi.org/10.1016/j.btre.2022.e00703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801760/
https://www.ncbi.nlm.nih.gov/pubmed/35145886
http://dx.doi.org/10.1016/j.btre.2022.e00703

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