Reproductive and developmental safety of nirmatrelvir (PF-07321332), an oral SARS-CoV-2 M(pro) inhibitor in animal models

Nirmatrelvir (PF-07321332; NMV) the antiviral component of PAXLOVID™ is a potent and selective inhibitor of the SARS-CoV-2 main protease (M(pro)), which plays a critical role in viral replication. PAXLOVID, comprised of nirmatrelvir and ritonavir (used as a pharmacokinetic enhancer), is an oral ther...

Descripción completa

Detalles Bibliográficos
Autores principales: Catlin, N.R., Bowman, C.J., Campion, S.N., Cheung, J.R., Nowland, W.S., Sathish, J.G., Stethem, C.M., Updyke, L., Cappon, G.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801796/
https://www.ncbi.nlm.nih.gov/pubmed/35101563
http://dx.doi.org/10.1016/j.reprotox.2022.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801796/
https://www.ncbi.nlm.nih.gov/pubmed/35101563
http://dx.doi.org/10.1016/j.reprotox.2022.01.006

Ejemplares similares