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DPHC From Alpinia officinarum Ameliorates Oxidative Stress and Insulin Resistance via Activation of Nrf2/ARE Pathway in db/db Mice and High Glucose-Treated HepG2 Cells

(R)-5-hydroxy-1,7-diphenyl-3-heptanone (DPHC) from the natural plant Alpinia officinarum has been reported to have antioxidation and antidiabetic effects. In this study, the therapeutic effect and molecular mechanism of DPHC on type 2 diabetes mellitus (T2DM) were investigated based on the regulatio...

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Detalles Bibliográficos
Autores principales: Zhang, Xuguang, Zhang, Yuxin, Zhou, Mingyan, Xie, Yiqiang, Dong, Xiujuan, Bai, Feihu, Zhang, Junqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801804/
https://www.ncbi.nlm.nih.gov/pubmed/35111058
http://dx.doi.org/10.3389/fphar.2021.792977