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Synthesis, Molecular Docking Analysis and in Vitro Biological Evaluation of Some New Heterocyclic Scaffolds-Based Indole Moiety as Possible Antimicrobial Agents

In the present study, a general approach for the synthesis of 1-(1H-indol-3-yl)-3,3-dimercaptoprop-2-en-1-one (1) and 5-(1H-indol-3-yl)-3H-1,2-dithiole-3-thione (2) was performed. They are currently used as efficient precursors for the synthesis of some new compounds bearing five- and/or six-membere...

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Detalles Bibliográficos
Autores principales: Hassan, Entesar A., Shehadi, Ihsan A., Elmaghraby, Awatef M., Mostafa, Hadir M., Zayed, Salem E., Abdelmonsef, Aboubakr H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801890/
https://www.ncbi.nlm.nih.gov/pubmed/35111810
http://dx.doi.org/10.3389/fmolb.2021.775013