High Throughput scRNA-Seq Provides Insights Into Leydig Cell Senescence Induced by Experimental Autoimmune Orchitis: A Prominent Role of Interstitial Fibrosis and Complement Activation

Leydig cells (Lc), located in the interstitial space of the testis between seminiferous tubules, produce 95% of testosterone in male individuals, which is pivotal for male sexual differentiation, spermatogenesis, and maintenance of the male secondary sex characteristics. Lc are prone to senescence i...

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Detalles Bibliográficos
Autores principales: Li, Yinchuan, Mi, Panpan, Wu, Jiabao, Tang, Yunge, Liu, Xiaohua, Cheng, Jinmei, Huang, Yingying, Qin, Weibing, Cheng, C. Yan, Sun, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801941/
https://www.ncbi.nlm.nih.gov/pubmed/35111154
http://dx.doi.org/10.3389/fimmu.2021.771373

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801941/
https://www.ncbi.nlm.nih.gov/pubmed/35111154
http://dx.doi.org/10.3389/fimmu.2021.771373

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