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Transactivation domain of Adenovirus Early Region 1A (E1A): Investigating folding dynamics and aggregation

Transactivation domain of Adenovirus Early region 1A (E1A) oncoprotein is an intrinsically disordered molecular hub protein. It is involved in binding to different domains of human cell transcriptional co-activators such as retinoblastoma (pRb), CREB-binding protein (CBP), and its paralogue p300. Th...

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Detalles Bibliográficos
Autores principales: Sharma, Nitin, Gadhave, Kundlik, Kumar, Prateek, Giri, Rajanish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801969/
https://www.ncbi.nlm.nih.gov/pubmed/35146445
http://dx.doi.org/10.1016/j.crstbi.2022.01.001