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Antiviral metabolite 3′-deoxy-3′,4′-didehydro-cytidine is detectable in serum and identifies acute viral infections including COVID-19

BACKGROUND: There is a critical need for rapid viral infection diagnostics to enable prompt case identification in pandemic settings and support targeted antimicrobial prescribing. METHODS: Using untargeted high-resolution liquid chromatography coupled with mass spectrometry, we compared the admissi...

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Detalles Bibliográficos
Autores principales: Mehta, Ravi, Chekmeneva, Elena, Jackson, Heather, Sands, Caroline, Mills, Ewurabena, Arancon, Dominique, Li, Ho Kwong, Arkell, Paul, Rawson, Timothy M., Hammond, Robert, Amran, Maisarah, Haber, Anna, Cooke, Graham S., Noursadeghi, Mahdad, Kaforou, Myrsini, Lewis, Matthew R., Takats, Zoltan, Sriskandan, Shiranee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8801973/
https://www.ncbi.nlm.nih.gov/pubmed/35128501
http://dx.doi.org/10.1016/j.medj.2022.01.009