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Impaired Light Adaptation of ON-Sustained Ganglion Cells in Early Diabetes Is Attributable to Diminished Response to Dopamine D4 Receptor Activation

PURPOSE: Retinal neuronal signaling is disrupted early in diabetes, before the onset of the vascular pathologies associated with diabetic retinopathy. There is also growing evidence that retinal dopamine, a neuromodulator that mediates light adaptation, is reduced in early diabetes. Previously, we h...

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Detalles Bibliográficos
Autores principales: Flood, Michael D., Wellington, Andrea J., Eggers, Erika D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802033/
https://www.ncbi.nlm.nih.gov/pubmed/35077550
http://dx.doi.org/10.1167/iovs.63.1.33