The autoimmune encephalitis-related cytokine TSLP in the brain primes neuroinflammation by activating the JAK2-NLRP3 axis

NLRP3 inflammasome hyperactivation contributes to neuroinflammation in autoimmune disorders, but the underlying regulatory mechanism remains to be elucidated. We demonstrate that compared with wild-type (WT) mice, mice lacking thymic stromal lymphopoietin (TSLP) receptor (TSLPR) (Tslpr(−/−) mice) ex...

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Detalles Bibliográficos
Autores principales: Yu, Xueyuan, Lv, Jiajia, Wu, Jun, Chen, Yong, Chen, Fei, Wang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802176/
https://www.ncbi.nlm.nih.gov/pubmed/35020848
http://dx.doi.org/10.1093/cei/uxab023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802176/
https://www.ncbi.nlm.nih.gov/pubmed/35020848
http://dx.doi.org/10.1093/cei/uxab023

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