Exosomes Secreted by Nucleus Pulposus Stem Cells Derived From Degenerative Intervertebral Disc Exacerbate Annulus Fibrosus Cell Degradation via Let-7b-5p

The pathogenesis of intervertebral disc degeneration (IDD) is complex and remains unclear. Nucleus pulposus stem cells (NPSCs) and annulus fibrosus cells (AFCs) play a critical role in the maintenance of intervertebral disc structure and function. Exosome-mediated miRNAs regulate cell proliferation,...

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Detalles Bibliográficos
Autores principales: Zhuang, Yin, Song, Sheng, Xiao, Dan, Liu, Xueguang, Han, Xiaofei, Du, Shihao, Li, Yuan, He, Yanming, Zhang, Shujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802296/
https://www.ncbi.nlm.nih.gov/pubmed/35111808
http://dx.doi.org/10.3389/fmolb.2021.766115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802296/
https://www.ncbi.nlm.nih.gov/pubmed/35111808
http://dx.doi.org/10.3389/fmolb.2021.766115

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