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Context dependency of nucleotide probabilities and variants in human DNA

BACKGROUND: Genomic DNA has been shaped by mutational processes through evolution. The cellular machinery for error correction and repair has left its marks in the nucleotide composition along with structural and functional constraints. Therefore, the probability of observing a base in a certain pos...

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Detalles Bibliográficos
Autores principales: Liang, Yuhu, Grønbæk, Christian, Fariselli, Piero, Krogh, Anders
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802520/
https://www.ncbi.nlm.nih.gov/pubmed/35100973
http://dx.doi.org/10.1186/s12864-021-08246-1