Systematic Determination of TCR–Antigen and Peptide–MHC Binding Kinetics among Field Variants of a Theileria parva Polymorphic CTL Epitope

CTLs are known to contribute to immunity toward Theileria parva, the causative agent of East Coast fever. The Tp9(67–75) CTL epitope from the Muguga strain of T. parva is polymorphic in other parasite strains. Identifying the amino acids important for MHC class I binding, as well as TCR recognition...

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Detalles Bibliográficos
Autores principales: Svitek, Nicholas, Saya, Rosemary, Zhang, Houshuang, Nene, Vishvanath, Steinaa, Lucilla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AAI 2022
Materias:
Antigen Recognition and Responses
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802549/
https://www.ncbi.nlm.nih.gov/pubmed/35031580
http://dx.doi.org/10.4049/jimmunol.2100400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802549/
https://www.ncbi.nlm.nih.gov/pubmed/35031580
http://dx.doi.org/10.4049/jimmunol.2100400

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