Cargando…
Systematic Determination of TCR–Antigen and Peptide–MHC Binding Kinetics among Field Variants of a Theileria parva Polymorphic CTL Epitope
CTLs are known to contribute to immunity toward Theileria parva, the causative agent of East Coast fever. The Tp9(67–75) CTL epitope from the Muguga strain of T. parva is polymorphic in other parasite strains. Identifying the amino acids important for MHC class I binding, as well as TCR recognition...
Autores principales: | Svitek, Nicholas, Saya, Rosemary, Zhang, Houshuang, Nene, Vishvanath, Steinaa, Lucilla |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AAI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802549/ https://www.ncbi.nlm.nih.gov/pubmed/35031580 http://dx.doi.org/10.4049/jimmunol.2100400 |
Ejemplares similares
-
Caveolin-1 Influences LFA-1 Redistribution upon TCR Stimulation in CD8 T Cells
por: Borger, Jessica G., et al.
Publicado: (2017) -
Peptide–MHC Class I Tetramers Can Fail To Detect Relevant Functional T Cell Clonotypes and Underestimate Antigen-Reactive T Cell Populations
por: Rius, Cristina, et al.
Publicado: (2018) -
Immunization with one Theileria parva strain results in similar level of CTL strain-specificity and protection compared to immunization with the three-component Muguga cocktail in MHC-matched animals
por: Steinaa, Lucilla, et al.
Publicado: (2018) -
Impaired NK Cell Responses to Pertussis and H1N1 Influenza Vaccine Antigens in Human Cytomegalovirus-Infected Individuals
por: Nielsen, Carolyn M., et al.
Publicado: (2015) -
Syk Tyrosine Kinase Is Critical for B Cell Antibody Responses and Memory B Cell Survival
por: Ackermann, Jochen A., et al.
Publicado: (2015)