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IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation

Insulin-like growth factor 2 (IGF2) mRNA-binding protein 2 (IGF2BP2) is an important posttranscriptional regulatory for stability and m6A modification. Here, we investigated the role of IGF2BP2 in non–small-cell lung cancer (NSCLC) proliferation. TCGA database was used to predict the expression and...

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Detalles Bibliográficos
Autores principales: Han, Le, Lei, Guangyan, Chen, Zhenghong, Zhang, Yili, Huang, Chen, Chen, Wenjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802805/
https://www.ncbi.nlm.nih.gov/pubmed/35111811
http://dx.doi.org/10.3389/fmolb.2021.780089